癫痫患者免疫球蛋白、补体C_3、循环免疫复合物含量与脑电图波形关系的研究  

RELATIONSHIP BETWEEN EEG AND MULTIPLE IMMUNE INDEXES IN EPILEPTIC PATIENTS

作　　者：杨均海[1] 王淑娟[1] 张增光[1] 申黎青[1] 刘忠强[1] 

机构地区：[1]青岛医学院附属医院神经病学研究室

出　　处：《青岛医学院学报》1991年第2期92-96,共5页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：观察了322例癫痫患者血清免疫球蛋白、补体C_3和循环免疫复合物(CIC)含量与脑电图波形的关系。结果发现,脑电图出现癫痫波形者较未出现癫痫波形者或对照组,其IgA平均含量显著降低(P<0.01),CIC平均含量显著增高(P<0.01),IgM平均含量轻度升高,这些变化与患者是否服用抗痫药物、发作类型及年龄等因素似无关系。其它所测免疫指标与脑电图不同波形之间比较无明显差异。提示癫痫放电波可能是造成癫痫患者某些免疫指标异常的重要原因之一。Relationship between electroencephalography (EEG) waveforms and serum mmunoglobin complement C_3 as well as circulating immune complexes (CIC) were observed in 322 epileptic patients. It was found that in patients who showed epileptic discharges in the EEG recordings, the mean IgA content was decreased significantly while the CIC content showed an obvious increase and the IgM a slight increase, as compared with those in the normal controls or patients who had no epileptic discharges. These changes seemed to have no relation to the taking of AEDS, the type of seizure, and the age of onset. It is common among patient, showing epileptic discharges to have decreased IgA and increased CIC. No othe difference in immune indexes were seen between the two patient groups. Thisr suggests that epiletic discharges may be an important factor that leads to abnormality of several immune indexes.

关 键 词：癫痫 脑电图 免疫球蛋白类 

分 类 号：R724.1[医药卫生—儿科]