肝血虚证15项实验指标同步检测的分析  

Simultaneously Analysis of 15 Parameters in the Patients With the Liver-Blood Deficiency Syndrome

作　　者：陈昌华[1] 石林阶[1] 舒毅刚[2] 陈国林[1] 邢之华[1] 张自强[1] 尤劲松[1] 

机构地区：[1]中南大学湘雅医院中西医结合研究所,长沙410008 [2]中南大学湘雅医院血液科,长沙410008

出　　处：《湖南医科大学学报》2001年第4期337-339,共3页Bulletin of Hunan Medical University

基　　金：国家自然科学基金重点资助项目 (No :33930 2 40 )

摘　　要：采用高效液相色谱 (HPLC -ED)法和放射免疫法 (RIA) ,对 2 7例肝血虚证患者 15项指标进行检测 ,经多因素聚类分析 ,并进行典型指标筛选。结果发现 :15项指标可聚五类 ,每类的典型指标分别为NE ,T3,TXB2 ,ALD和cGMP。提示肝血虚证的病理基础主要以交感神经活动减退 ,低T3 综合征 ,调节心血管舒缩和水盐代谢的活性物质以及细胞膜内第二信使类物质的显著改变为特征。Objective Using HPLC-ED or RIA, we determned simultaneously 15 indexes in 27 patients with the liver-blood deficiency syndrome (LDBD). By means of multivarivate hierarchical cluster analysis and selections of typical variate, the results showed that 15 indexes were classified into 5 groups, and the typical variates of each groups were NE, T 3, TXB 2, ALD and cGMP. It suggests that LBDS has some pathopysiologyical characteristics such as decreased functions of sympatehetic nerve activation, lower T 3 syndrome, imbalance of the active substance regulating cardiovascular function and metabolism of salt and water, and abnormalities second signal substance in cellular membrane.

关 键 词：肝血虚证 低色素性贫血 再生障碍性贫血 病理生理学 多元分析 聚类分析 RIA HPLC-ED 

分 类 号：R241[医药卫生—中医诊断学]