系数倍率法测定舒尔芬片中两组分的含量  

Determination of codeine phosphate and diclofenac sodium in Shuerfen tablet by k-ratio method

作　　者：徐楚鸿[1] 陈东生[1] 王虎[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院,湖北武汉430022

出　　处：《中国医院药学杂志》2001年第10期604-605,共2页Chinese Journal of Hospital Pharmacy

摘　　要：目的：建立舒尔芬片的含量测定方法。方法：采用系数倍率分光光度法,消除共存组分的干扰。结果：被测两组分的吸收度差值与浓度有良好的线性关系，3个模拟样品的平均回收率和RSD分别为 磷酸可待因97.17%,0.57%;双氯芬酸钠100.89%,0.89%。结论：该方法简便、准确,可用于舒尔芬片的质量控制。OBJECTIVE To establish a method for determination of two components in Shuerfen table t. METHODS The K-ratio method was applied in this paper. RESULTS The average recoveries and relative standard devia tions of two components in three model simples were 97.17％,0.57％ for codeine phosphate and 100.89％,0.89% for diclofenac sodium separately. CONCLUSIONS The method was simple and accurate,and could be used for the quality contr ol of shuerfen tablet.

关 键 词：系数倍率法 双氯芬酸钠 磷酸可待因 舒尔芬片 含量 质量控制 

分 类 号：R971.1[医药卫生—药品] R927.11[医药卫生—药学]