轮状病毒弱毒疫苗田间效力试验  

EFFICACY OF ATTENUATED VACCINE AGAINST ROTAVIRUS IN FIELD TEST

作　　者：叶成玉[1] 周尚志[1] 程庆华[1] 牛小迎[1] 乔司仁 严生旺 

机构地区：[1]青海省畜牧兽医科学院 [2]乌兰县畜牧兽医站

出　　处：《青海畜牧兽医杂志》1991年第5期1-2,共2页Chinese Qinghai Journal of Animal and Veterinary Sciences

摘　　要：1988—1989年产羔期在青海省乌兰县对自制的轮状病毒弱毒疫苗进行了田间效力试验。试验结果表明:口服轮状病毒弱毒疫苗和复方敌菌净的初生羔的腹泻发病率为1.96％,死亡率为0.31％,成活率为99.69％;单用复方敌菌净的初生羔上述指标分别为14.89％,11.23％和88.77％;而不进行任何处理的对照组初生羔的腹泻死亡率为47.37％,存活率为52.63％,从而证实该疫苗能有效地预防初生羔腹泻,且有安全和吮吸初乳前后均可使用的优点,建议在疫区大面积推广使用。In 1988-1989, the efficacy of an attenuated vaccine against rotavirus, which prepared in our laboratory, was evaluated in field test in Wulan county, Qinghai province during lambing season. The results showed that the incidence of diarrhea, mortality and survival rate of newborn lambs were 1.96%, 0.31% and 99.69%, resp., in the newborn lamb group administered per os the attenuated vaccine against rotavirus and a Co-Diaveridine, but in the group administered alone the Co-Diaveridine—14.89%, 11.23% and 88.77%, and in the control untreated lamb group, the mortality of the iambs with diarrhea was 47.37% and survival rate was 52.6%. It was concluded that this attenuated vaccine against rotavirus may effectively prevent the diarrhea of newborn lambs and has an advantage safety and effection in both iambs sucked and unsucked the colostrum. There was a recommendation that would be use and popularize this vaccine in the epidemic region.

关 键 词：轮状病毒 弱毒疫苗 田间 防疫 试验 

分 类 号：S852.65[农业科学—基础兽医学]