两种硝酸异山梨酯注射液治疗心绞痛的疗效观察  

Clinical Efficacy of Two Kinds of Intravenous Isosorbide in Treatment of Angina Pectoris

作　　者：李晓燕[1] 李爱国[1] 雷著斌[1] 杨绍祥[1] 卫亚[1] 

机构地区：[1]解放军济南军区总医院心内科,山东济南250031

出　　处：《临床军医杂志》2001年第4期16-17,共2页Clinical Journal of Medical Officers

摘　　要：目的　比较两种硝酸异山梨酯静脉制剂 ,进口异舒吉 (Isoket)及国产爱倍 (ISDN) ,治疗心绞痛的效果。方法　采用随机、单盲的方法 ,将 145例心绞痛病人分为两组。分别给予异舒吉或爱倍注射液 2 0mg ,测定用药前、后血压、心率及心电图变化。结果　两组药物治疗心绞痛有效率分别为 48 6 1%和 5 0 6 8% ,总有效率为 98 6 1%和 98 6 3%。两组疗效均显著 ,均降低血压 ,心率 ,改善心肌缺血 ,组间无显著差异。结论　两组药物治疗心绞痛疗效相似。Objective To compare the effects of imported isosorbide dinitrate(Isoket)and domestic isosorbide dinitrate(Aibei)injection on patients with angina pectoris. Methods Using a randomized single-blind design, one hundred and forty-five patients were divided into two groups. 20 mg Isoket or Aibei injection was given. Blood pressure, heart rate and Electrocardiogram were carried out after and before the two groups patients accepted the treatment. Results The response rates were 48.61% and 50.68%, and the total effective rates were 98.61% and 98.63% respectively. They both declined blood pressure and heart rate and improved myocardial ischemic there was not a significant difference between the two group( P >0.05). Conclusion Two kinds of intravenous isosorbide were equivalent in the treatment of patients with angina pectoris.

关 键 词：磷酸异山梨酯 心绞痛 血压 心电图 

分 类 号：R541.4[医药卫生—心血管疾病] R972.3[医药卫生—内科学]