心房颤动与脑白质疏松症的关系  

Association between Leukoaraiosis and Atria Fibrillation

作　　者：李庆华[1] 王玉敏[1] 唐静怡[1] 欧阳文[1] 齐丽娟[1] 

机构地区：[1]解放军白求恩国际和平医院干部病房,河北石家庄050082

出　　处：《临床军医杂志》2001年第3期23-25,共3页Clinical Journal of Medical Officers

摘　　要：目的　探讨心房颤动与脑白质疏松症 (LA)的关系。方法　选择 1 86例老年LA患者 ,并按 1∶1配对的病例对照研究 ,对其相关因素如 :有无心房颤动、高血压病、心肌梗塞、左室肥厚、既往缺血性脑血管病史等进行调查。结果　在单因素分析中 ,心房颤动在LA组的发病率显著高于无LA组 (1 4.0 %及 7 0 % ,P =0 .0 2 8)。在多因素Logistic回归分析中 ,经高血压病 ,缺血性脑血管病及左室肥厚等因素调整后心房颤动仍与老年LA显著相关 (OR =2 .2 0 ;95 %可信区间 1 .0 6～ 4.5 7;P =0 .0 3 5 )。结论　心房颤动可能为老年LA独立的危险因素。Objective To investigate whether atria fibrillation (AF) is an risk factor for leukoaraiosis (LA) in older persons. Methods 186 patients with or without LA were investigated. We analysed the clinical features such as the age, histories of AF, hypertention, previous stroke or transient ischemic attacks, left ventricular hypertrophy and myocardial infarction. Results In the univariate analysis, The prevalence of AF in the study group was significantly higher (14.0%) than in the control group (7.0%; P=0.028), multivariate analysis revealed that AF is a significant risk factor when adjusted for confounding factors, including hyertension, previous stroke or transient ischemic attacks, left ventricular hypertrophy (OR=2.20; 95% CI, 1.06～4.57; P=0.035). Conclusion AF is an risk factor for LA in older persons.

关 键 词：脑白质疏松症 心房颤动 危险因素 LA 

分 类 号：R541.7[医药卫生—心血管疾病] R743.9[医药卫生—内科学]