慢性心力衰竭患者血清铁蛋白的测定及其临床意义  

A study on the serum ferroprotein levels and its clinical significance in chronic heart failure

作　　者：陈成龙[1] 季乃军[1] 陈东海[1] 王成尧[1] 梅益斌[1] 方宗桥[1] 樊必夫[1] 徐俊龙[1] 

机构地区：[1]丽水市人民医院心内科,浙江省丽水市323000

出　　处：《心血管康复医学杂志》2001年第1期22-24,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的 :探讨慢性心力衰竭患者血清铁蛋白的变化及其临床意义。方法 :采用放射免疫法测定 110例慢性心力衰竭患者血清铁蛋白 (SF)水平 ,并与 2 5例健康组相对照。结果 :慢性心力衰竭患者 SF显著高于对照组 (P<0 .0 5 ) ,其中合并感染组显著高于无感染组 (P<0 .0 1) ,合并心脏恶液质综合征者显著低于无该合并症者 ,随心力衰竭的加重 , 、 、 度心力衰竭组间 SF依次显著递减 (P<0 .0 1)。结论 :对慢性心力衰竭患者进行 SF的监测 ,有助于对疾病严重程度和预后的判断。Objective:To study the changes of the serum ferroprotein(SF)levels in patients with chronic heart failure (CHF),and its clinical significance.Methods:The SF levels were determined by radioimmunoassay in 110 patients with CHF and 25 healthy individual(control).Results:The mean serum SF level in patients with CHF(290 68±23 20 mg/L) significantly heighten than in control group (190 60±15 69mg/L)( P <0 05).The differences of mean SF levels were significant among different degrees(Ⅰ、Ⅱ、Ⅲdegree)( P <0 01).In infected CHF patients,the mean level of the SF significantly heighten than in no\|infected CHF patients( P <0 01),and the mean level of the SF in CHF patients with syndrome of cardiac cachexia,was significantly lower than in patients without syndrome of cardiac cachexia.Conclusion:Determined the levels of the SF may be aided to estimated the severity and prognosis of the CHF.

关 键 词：心力衰竭 铁蛋白 放射免疫法 

分 类 号：R541.6[医药卫生—心血管疾病]