静脉注射维拉帕米或普罗帕酮治疗阵发性室上性心动过速的对比研究  

Comparison between Intravenous Verapamil or Propafenone in Treating Paroxysmal Supraventricular Tachycardia

作　　者：康凯[1] 曹珍菊[1] 戚立菊[1] 刘爱军[1] 马锦森[1] 

机构地区：[1]滨海县人民医院心内科,江苏滨海224500

出　　处：《镇江医学院学报》2001年第4期444-445,共2页Journal of Zhenjiang Medical College

摘　　要：目的 :观察静脉注射维拉帕米或普罗帕酮治疗阵发性室上性心动过速 (PSVT)的疗效。方法 :静脉注射维拉帕米治疗 35例 78例次PSVT ,并与普罗帕酮治疗 31例 59例次PSVT对比观察。结果 :维拉帕米组总例次终止率为 89.7% ,普罗帕酮组总例次终止率为 88.7%。两组疗效、终止PSVT发作的心电图形式等无显著性差异 (P >0 .0 5)。普罗帕酮组 2例较长时间窦性停搏 ,1例致Ⅲ度房室传导阻滞 (AVB) ,3例中 2例死亡。结论 :房室结折返性心动过速 (AVNRT)应用维拉帕米复律优于普罗帕酮 (P <0 .0 5)。普罗帕酮副作用较大。Objective:To study the effects of intravenous verapamil or propafenone in paroxysmal supraventricular tachycardia(PSVT).Methods:35 patients with 78 episodes of PSVT were treated with intravenous verapamil and the other 31 patients with 59 episodes of PSVT were treated with intravenous propafenone. Results:It has been shown that the termination rate of PSVT was 89.7% in verapamil group and 88.1% in propafenone group respectively. There is no difference between the two groups with regard to the effectiveness of treatment and the terminated ECG type( P >0.05).Two cases in propafenone group suffered from sinus arrest for a long time and one case suffered from Ⅲdegree OAVB,among whom two died.Conclusion:In AVNRT group verapamil is better ( P <0.05).There are serions side reactions in propafenone.

关 键 词：维拉帕米 普罗帕酮 治疗 室上性心动过速 静脉注射 

分 类 号：R541.710.5[医药卫生—心血管疾病]