孔雀绿与CTAB胶束的相互作用  

Interaction of Malachite Green with CTAB Micelles

作　　者：郭荣[1] 刘薇娅[1] 范国康[1] 

机构地区：[1]扬州大学化学系,扬州225002

出　　处：《物理化学学报》2001年第12期1062-1066,共5页Acta Physico-Chimica Sinica

基　　金：国家自然科学基金(29733110;20073038);教育部优秀骨干教师资助项目

摘　　要：以ＣＴＡＢ胶束模拟生命体系，用ＵＶ－Ｖｉｓ和荧光光谱等技术研究了孔雀绿与ＣＴＡＢ胶束的相互作用，结果表明，孔雀绿自发地定位于ＣＴＡＢ胶束栅栏层，使得胶束聚集数增加，胶束的微环境极性Ｉ１／Ｉ３下降．孔雀绿与ＣＴＡＢ胶束之间的结合常数Ｋ和孔雀绿在胶束相与水连续相之间的分配系数ＫＤ均随孔雀绿浓度增加而降低，表明孔雀绿与ＣＴＡＢ胶束之间的相互作用随孔雀绿浓度增加而降低．The interaction between malachite green (MG) and cetyltrimethyl ammonium bromide (CTAB) micelle simulating life system has been studied in the CTAB micelle using UV-Vis and fluorescent spectra. The results show that MG can locate in the palisade of CTAB micelle spontaneously, which leads to the increase of the aggregation number (N) and the decrease of the micro-polarity ( I-1/I-3 ) of CTAB micelle. Both of the binding constant K of MG with CTAB micelle and the distribution coefficient K-D of MG between the CTAB micelles and the aqueous phase decrease with the increase of the concentration of MG. These results indicate that the interaction between MG molecules and CTAB micelles decreases with the increase of MG concentration.

关 键 词：孔雀绿 胶束 CTAB 生物模拟 结合常数 十六烷基三甲基溴化铵 相互作用 临床药理 生命体系 皮肤病药物 

分 类 号：O648.1[理学—物理化学]