眼烧伤的激素治疗  

Treatment of the ocular burn with hormone

作　　者：韩春茂[1] 姚玉峰[2] 余朝恒[1] 

机构地区：[1]浙江大学医学院附属第二医院烧伤科,杭州310009 [2]浙江大学医学院邵逸夫医院眼科

出　　处：《中华烧伤杂志》2001年第6期330-332,共3页Chinese Journal of Burns

摘　　要：目的　为改善眼球烧伤预后差的现状 ,观察激素治疗眼球烧伤的新方法。　方法　激素治疗组 :1997～ 2 0 0 0年眼球烧伤的入院患者 12例 (18只眼 ) ,常规加皮质激素和人重组生长激素治疗 ,皮质激素伤后立即开始 ,全身与局部同时应用 ,疗程 2～ 4周。生长激素伤后 1周开始 ,持续 2周。对照组 :1993～ 1996年的住院患者 9例 (12只眼 ) ,常规治疗眼球烧伤。比较两组治疗方法的效果。　结果　激素治疗组 12例患者烧伤眼球全部愈合 ,溃疡和穿孔发生少 ,视力恢复良好 ,较对照组明显改善。　结论　皮质激素和人重组生长激素联合应用 。Objective To explore new ways of the management of ocular burn with the use of hormones ( human growth hormone and corticosteroid). Methods Twenty-one patients (30 eyes) with ocular burn were enrolled in the study. Nine cases (12 eyes) were treated with routine methods. while in 12 cases (18 eyes) corticosteroid and recombinant human growth hormone (rhGH) were used. The corticosteroid was applied immediately postburn both systemically and topically and continued for 2～4 weeks. But the rhGH was applied after 1 week postburn and continued for 2 weeks. The results in the above two groups were compared . Results Compared with those in control group, all the 18 eyes in the 12 patients with ocular burn were saved and cured with the trealments of hormones. There was significantly less incidence of corneal ulceration and perforation and better visual recovery in those treated with the hormones. Conclusion Combined application of corticosteroid and rhGH might be beneficial to the management of patients with ocular burn.

关 键 词：糖皮质激素类 生长激素 眼烧伤 伤口愈合 

分 类 号：R644[医药卫生—外科学] R779.1[医药卫生—临床医学]