二茂铁亚胺环钯化合物在Heck反应中的催化活性研究  

Studies on the Catalytic Activity of Cyclopalladated Ferrocenylimines in Heck Reaction

作　　者：吴养洁[1] 侯建军[1] 廖新成[1] 

机构地区：[1]郑州大学化学系,

出　　处：《化学学报》2001年第11期1937-1941,共5页Acta Chimica Sinica

基　　金：国家自然科学基金，河南省自然科学基金

摘　　要：二茂铁亚胺环钯化合物1和2催化Heck反应具有底物范围广、反应条件温和、不需要惰性气体保护、催化活性高、重复使用仍能保持活性的特点.芳基碘化物、溴化物和氯化物都可作为反应底物.化合物2应用于碘苯和丙烯酸丁酯的反应得到了92%的产率和7 360000的转化数;应用于碘苯和丙烯酸乙酯的偶联反应,反复使用五次仍然保持很高的活性.利用高压液相色谱或薄层色谱监测反应.A novel kind of ferrocene moieties containing palladacycle catalysts 1 and 2 was synthesized and applied to Heck reaction. It was characterized by a wide variety of substrates, mildness of reaction conditions, freedom from protection of inert gases and high catalytic activity retainable after repeated uses. When catalyst 2 was used to catalyze the coupling of iodobenzene with butyl acrylate, optimal results were obtained with 7 360 000 turnover number and 92% yield. The catalyst 2 could be reused at least five times in the coupling of iodobenzene with ethyl acrylate. Some of the reactions were followed by HPLC.

关 键 词：二茂铁亚胺环钯化合物 HECK反应 催化剂 烯烃 芳基化 催化活性 有机合成 

分 类 号：O621.36[理学—有机化学] O643.36[理学—化学]