电针对脑血栓急性期纤溶功能的影响  

The Influence of Electroacupuncture on the Function of Fibrinolysis in Patients with Acute Cerebral Thrombosi

作　　者：钟池[1] 周立忠[1] 路建平[1] 罗宁[1] 李世荣[1] 

机构地区：[1]复旦大学医学院附属华山医院神经病学研究所,上海200032

出　　处：《浙江中西医结合杂志》2001年第12期737-739,共3页Zhejiang Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的 :观察电针治疗对脑血栓形成急性期纤溶功能的影响及其与临床转归之间的关系。方法 :采用头、体针结合电针进行治疗。用发色底物法测定治疗前、后患者血浆组织型纤溶酶原激活物 (t- PA)及其快速抑制物 (PAI- 1)的活性。于治疗前、后进行神经功能缺损评分 ,并与一般治疗方法作对照。结果 :急性脑血栓形成患者电针治疗后血浆 t- PA活性明显高于对照组 ,P<0 .0 1;PAI- 1活性明显低于对照组 ,P<0 .0 1;神经功能缺损评分明显低于对照组 ,P<0 .0 1。结论 :脑血栓形成急性期头、体穴位结合电针治疗能明显提高血浆 t- PA活性 ,降低 PAI- 1水平 ,促进纤溶功能 。Objective:To observe the influence of electro acupuncture on the function of fibrinolysis in patients with acute cerebral thrombosis and it's relation with the clinical result.Methods:26 patients with acute cerebral thrombosis were treated with electroacupuncture at the points on head and limbs,25 cases were cured with usual methods only.Tissue type plasminogen activator (t PA) and plasminogen activator inhibitor (PAI 1) were assayed by ELISA at the begining and the ending of the treatment. Results: In patients with acut ecerebral thrombosis treated with electroacupuncture,the level of t PA was significantly higher and that of PAI 1 was significantly lower than those of controls at the end of the treatment.Conclusions:The electroacupuncture on the patients with acute cerebral thrombosis at the points on head and limbs raises the level of t PA,cuts down the level of PAI 1 and improves the plasma fibrinolytic activity.The acupuncture mechanism of treating acute cerebral thrombosis relates to regulating rebalance of “t-PA-PAI 1 system” .

关 键 词：脑血栓形成 电针 组织型纤溶酶原激活物 纤溶酶原激活物抑制物 神经功能 

分 类 号：R245.97[医药卫生—针灸推拿学]