医院感染败血症危险因素探讨  

An Approach to Nosocomial Infection as a Risk Factor of Septicemia

作　　者：王翠兰[1] 李志军[1] 卓和平[1] 李成云[1] 董泽润[1] 

机构地区：[1]蚌埠医学院附属医院,安徽蚌埠233004

出　　处：《中华医院感染学杂志》2001年第5期321-323,共3页Chinese Journal of Nosocomiology

摘　　要：目的　探讨医院感染败血症的危险因素及防治措施。方法　对 1993年 3月～ 1999年 3月经血或骨髓培养证实的 130例医院感染败血症的危险因素与同期随机抽取的 130例社会感染败血症进行比较 ;进行单因素 χ2 检验 ,对有显著差异的危险因素用非条件 L ogistic逐步回归法进行多因素分析。结果　住院时间 >3周、侵入性操作、有中枢神经系统损害及应用细胞毒免疫抑制剂等 5项是医院感染败血症发生的主要危险因素。结论　有上述危险因素存在的患者要严密监测有无感染发生 ,缩短住院时间 ;尽量减少插用导尿管及其他插管 ;加强中枢神经系统疾病患者的护理 ;谨慎应用细胞毒免疫抑制剂均可减少医院感染败血症的发生。OBJECTIVE To investigate nosocomial infection as a risk factor of septicemia and its treatment measures. METHODS To make a comparison between the 130 cases of septicemia infected in hospitalization during 1993 1999 and confirmed by blood and marrow cultures, and the random 130 cases of septicemia contracted before admission. First, monovariable χ 2 test was conducted, and then non condition Logistic regression analysis of the markedly different factors in the two groups was employed.RESULTS The five major risk factors may be involved in infecting septicemia, including the duration of hospitalization for over 3 weeks, use of catheters, use of intubates, damage to central nervous system and administration of immuno inhibitor of cytotoxins.CONCLUSIONS The patients related to the 5 major factors should be strictly detected to find out if any infection occur in them.It is suggested that precautions against hospital infection septicemia such as shortening the duration of hospitalization, reducing use catheters, strengthening nursing the patients with the diseases of central nervous system and cautiously using immuno inhibitor of cytotoxins be taken so as to reduce the incidence of the disease.

关 键 词：医院内感染 败血症 危险因素 流行病学 

分 类 号：R515.301[医药卫生—内科学]