氯沙坦钾与卡托普利对高血压左心室肥厚逆转作用的比较  

Comparison of Left Ventricular Hypertrophy Regression after Treatment Using Losartan and Captopril in Patients with Hypertension

作　　者：叶向阳[1] 龚铭[1] 童步高[2] 

机构地区：[1]浙江省瑞安市人民医院心内科,瑞安325200 [2]复旦大学附属中山医院,上海200032

出　　处：《中国临床医学》2001年第5期498-499,共2页Chinese Journal of Clinical Medicine

摘　　要：目的 :研究科素亚逆转高血压患者左室肥厚的作用。方法 :分别对 39名高血压病人用科素亚及 35名高血压病人用卡托普利治疗 6个月。观察治疗前后的血压及室间隔厚度 (IVS) ,左心室后壁厚度 (PWT) ,左心室心肌重量 (LVM) ,左心室重量指数 (LVMI)等指标的变化。结果 :两组经治疗后血压及IVS ,PWT ,LVM ,LVMI等指标均有明显的改善。结论Objective: To study the regressive effect on left ventricular hypertrophy(LVH) by antihypertensive drugs losartan and captopril. Method: 39 patients were treated with losartan and 35 were treated with captopril for 6 months. Blood pressure and interventricular septum(IVS),posterior wall thickness(PWT), left ventricular mass(LVM),left ventricular mass index(LVMI) were examined before and after treatment. Results: After 6 months treatment with losartan and captopril, blood pressure and IVS, PWT, LVM, LVMI were decreased obviously in both groups. Conclusion: Captopril and losartan have similar regressive effect on LVH of hypertension.

关 键 词：高血压 利素亚 卡托普利 左心室肥厚 

分 类 号：R544.1[医药卫生—心血管疾病]