对甲氧基甲苯氨氧化反应研究  

The Research on the Ammoxidation of p-methoxytoluene

作　　者：谢光勇[1] 郑穹[1] 黄驰[1] 韩其勇[1] 陈远荫[1] 

机构地区：[1]武汉大学化学与分子科学学院,湖北武汉430072

出　　处：《武汉大学学报（理学版）》2001年第6期685-688,共4页Journal of Wuhan University:Natural Science Edition

摘　　要：研究了用 VPO/ Si O2 催化剂由对甲氧基甲苯 (PMOT)制备大茴香腈 (PMOBN)的氨氧化反应 .在内径 2 0 mm的石英管固定床反应器上 ,分别采用正交设计法实验和单因素实验考察了反应温度、空气比、氨气比、空间速度以及催化剂活性组分中的不同磷钒比 (P/ V)对 PMOT转化率、PMOBN摩尔产率和选择性的影响 .确定最适宜的反应条件是 :P/ V为 1,温度 6 0 3K,反应物摩尔比 n(PMOT)∶ n(NH3 )∶ n(Air) =1∶ 12∶ 30 ,空间速度 5 6 4h- 1 .在此条件下 ,PMOT转化率 98%,PMOBN摩尔产率 6 3%,选择性 6 4.3%.经气相色谱分析 ,产品纯度高于 99%.Anisonitrile has been prepared by ammoxidation of p-methoxytoluene over VPO/SiO 2 catalyst. The orthogonal tests of reaction conditions and evaluation tests of catalysts were carried out in a 20 mm inside diameter fixed-bed quartz reactor. The influences of reaction temperature, the ratio of ammonia, the ratio of air, the space velocity and different rate of phosphorus and vanadium (P/V) in the catalyst upon the conversion, molar yield and selectivity of the reaction were studied. The optimum reaction conditions are: the ratio of P and V is 1, the temperature is 603 K, n(PMOT)∶n(NH 3)∶n(Air)=1∶12∶30 and the space velocity is 564 h -1 . Under these conditions, the conversion of PMOT is 98%, the molar yield of PMOBN is 63% and selectivity is 64.3%. The purity of product is over 99% by GC.

关 键 词：氨氧化反应 对甲氧基甲苯 大茴香腈 VPO/SiO2催化剂 正交设计 对甲氧基苯腈 反应条件 

分 类 号：O625.67[理学—有机化学] O621.254.1[理学—化学]