上海市妊娠合并梅毒现况调查  

Study on Pregnancy Complicated Syphilis in Shanghai

作　　者：王丽珍[1] 朱丽萍[1] 钱尚萍[1] 陈如钧[1] 王哲蔚[1] 

机构地区：[1]上海市第一妇婴保健院上海市妇女保健所,200040

出　　处：《中华围产医学杂志》2001年第4期205-208,共4页Chinese Journal of Perinatal Medicine

摘　　要：目的　了解上海市妊娠合并梅毒的发生率及其影响因素 ,为采取对策提供依据。　方法　采用现况调查方法 ,对象是 1999年 9月 2 0日至 12月 2 0日在本市 2 9所医院产前检查和住院分娩的所有孕产妇。调查内容包括、婚育史、实验室检查与患者治疗、妊娠结局及其新生儿实验室检查等。　结果　 12 32 4例孕妇中妊娠合并梅毒 39例 ,发生率为 3.16‰ ,均为早期梅毒 ,其中潜伏梅毒35例占 89.7% ; 期梅毒 3例占 7.7% ; 期梅毒 1例占 2 .6 %。患者平均年龄 (2 7± 5 )岁。与梅毒发生的相关因素有夫妇的文化程度、职业、婚前医学检查时梅毒的阳性结果以及孕妇本人的性伴数和户口所在地等。接受治疗者仅占 6 4.1% ,新生儿接受血清学检查者仅 48.7%。　结论　上海市妊娠合并梅毒的发生率较高 ,以潜伏梅毒为主 ,分布广 ,危害大 ,治疗和随访不规范 。Objectives To learn the incidence and the related factors of pregnancy complicated syphilis and provide basis for policy making. Methods A cross sectional study was carried out for all pregnant women who were checked up in 29 hospitals of Shanghai and delivered between 20th, Sep. to 20 th, Dec. in 1999. Basic condition, marital and obstetric history, lab test, treatment, pregnancy outcomes and lab test on neonate were investigated. Results There were 39 cases of pregnancy complicated syphilis among 12 324 pregnant women, with an incidence of 3.16‰. All cases were in early stage. Among them, 35 cases were latent syphilis, which accounted for 89.7%; 3 cases (7.7%) were primary syphilis; 1 case (2.6%) was secondary syphilis. The average age of the patients was (27±5) years old. The related factors included: couple's education, occupation, the lab index of syphilis at premarital medical examination, the number of sexual partners of pregnant women and residential area. Only 64.1% of partuients received treatment and 48.7% of infants received serological test. Conclusions the incidence of pregnancy complicated syphilis was relatively high and most cases were latent syphilis which were widely dispersal and had adverse sequelae on fetus and neonates; The treatment and followup were not standardized. So it is in urgent need to advocate the standardized treatment and followup for pregnancy complicated syphilis. It's also important to educate among the doctors, nurses in gynecologic & obstetric department and women at their reproductive age on the knowledge about prevention and treatment on syphilis.

关 键 词：梅毒 感染性 发病率 妊娠合并症 影响因素 

分 类 号：R714.25[医药卫生—妇产科学]