米索前列醇配伍安定在计划分娩中的临床应用研究  

A clinical study of Misoprostol with Diazepam in delivery planning

作　　者：郑永玲[1] 陈东辉[1] 王翠华[1] 丁茜[1] 王珠芬[1] 

机构地区：[1]莱芜市人民医院,莱芜271100

出　　处：《贵州医药》2001年第12期1080-1081,共2页Guizhou Medical Journal

摘　　要：目的总结 1999年 6月至 2 0 0 0年 9月对 15 2例孕妇开展计划分娩的经验。方法将 45 0例足月孕妇分为米索前列醇配伍安定 (联合 )组 15 2例 ,蓖麻餐组 148例 ,自然分娩组 15 0例。联合组于凌晨 4时口服 5 0 μg米索 ,同时静推安定 10mg ,以后每间隔 5h ,阴道后穹隆放置 5 0 μg。蓖麻餐组用蓖麻油 5 0ml+2个鸡蛋煎服。结果 (1)引产效果 :联合组成功率为 92 % ,蓖麻餐组为 45 8% ,P <0 0 1。(2 )产程 :计划分娩产程明显短于自然分娩 ,联合组更为明显 ,总产程比自然分娩缩短 4 5h。 (3)母婴并发症 :计划分娩于自然分娩差异均有显著性 ,P <0 0 1。结论米索配伍安定用于计划分娩可缩短产程 ,降低母婴并发症 ,能有计划的控制分娩 ,便于产时监护 ,同时避免过期妊娠。Objective To study the clinical significantion of delivery planning with misoprostol and diazepam. Methods 450 normal term pregnant women from 1999.6 to 2000.9 were assigned group A:misoprostol with diazepam(152 cases), group B:castoroil group(148 cases), and group C:natural labor (150 cases) as control. In group A, each patient be taken orally misprostol 50μg, injected 10mg diazepam and then be give misprostol 50μg through poterior vaginal for every 5hrs. In group B, casteroil 50ml add two fried eggs be taken orally together. Results The success rate of induced labor in group A was 92%, group B 45.8% ( P <0.01). The birth process of planned labor was much shorter than natural labor group, and the group A was the shortest. The complication to baby and the parent: There was significant difference in planned group and natural labor group ( P <0.01). Conclusion Using misoprostol with diazepam to delivery planning will shorten the birth process, prevent complication, adjust delivery systematically.

关 键 词：计划分娩 米索前列醇 安定 

分 类 号：R979.2[医药卫生—药品] R714.3[医药卫生—药学]