单扫描极谱法测定天然麝香中的麝香酮  

DETERMINATION OF MUSCONE IN MUSK BY SINGLE SWEEP POLAROGRAPHY

作　　者：何易玲 汤晓勤[2] 向仕学[2] 徐佳 

机构地区：[1]四川省峨眉山市卫生防疫站,四川峨嵋614200 [2]四川省卫生防疫站,四川成都610031 [3]乐山市五通桥区防疫站,四川乐山614800

出　　处：《华西药学杂志》2002年第1期53-54,共2页West China Journal of Pharmaceutical Sciences

摘　　要：目的　建立天然麝香中麝香酮的含量测定方法。方法　样品用乙醇浸提 ,在 0 2 5g·L-1盐酸苯肼 - 1 0g·L-1氯化钠底液中 ,于峰电位 - 80 0mV(vs.SCE)处测定麝香酮。结果　麝香酮含量在 2 5～ 2 0 μg范围内线性关系良好 ,r =0 9995 ,方法检出限为 1 5 μg ,日内精密度 RSD =6 4 % (n =5 ) ,日间精密度RSD =7 0 % (n =5 ) ,平均回收率为 89 7%。结论　该方法快捷、简便易行。OBJECTIVE To establish a single sweep polarography for determining Muscone in musk.METHODS The samples were extracted with alcohol;Muscone in musk was determined by the Single sweep polarography in 0.25 g·L -1 phenylhydrazine-1.0 g·L -1 sodium chloride solution at peak potential-800 mV (vs.SCE).RESULTS The linear retationship for muscone was good(2.5-20 μg).The relative coefficient was 0.9995.The detectability of the method is 1.5 μg.RSD in a day was 6.4%(n=5)and RSD between days was 7.0%(n=5).The average recovery was 89.7%.CONCLUSION The method is simple,rapid and easy for the determination of muscone in musk.

关 键 词：极谱法 麝香酮 天然麝香 含量测定 

分 类 号：R282.74[医药卫生—中药学] R284.1[医药卫生—中医学]