疏水作用色谱用球状交联聚乙烯醇的制备  

Synthesis of Cross-Linked Polyvinyl Alcohol Beads for hydrophobic interaction chromatography

作　　者：匡科[1] 钟振声[1] 穆筱梅[1] 

机构地区：[1]华南理工大学化学系,广州510640

出　　处：《广东化工》2001年第5期16-17,25,共3页Guangdong Chemical Industry

摘　　要：采用悬浮聚合法成功地制备了PVA白球。本文对水溶液中PVA含量、甲醛用量、表面活性剂、油水体积比、搅拌速度及反应温度等影响因素进行了研究和探索。实验得到了最佳工艺条件为:50ml 15％PVA分散在300ml的油相中,以3.0g油酸钠和5.0ml Span-80作表面活性剂,用10 ml甲醛溶液作交联剂,在88℃和400 r/min的条件下进行悬浮聚合,制备得到了缩醛化度为30％的球状PVA颗粒,其中粒径0.30～0.45mm(40～60目)者约占80％。The polymeric beads of PVA were successfully synthesized in transformer oil by suspended polymerization. The factors such as the polymerization degree and concentration of PVA, the amount of formaldehyde, phase ratio, stirring speed and temperature were thoroughly studied in this paper. The best synthetic conditions were follows: content of PVA was 15% , sur-face-active agent was 30. g sodium oleate and 5.0ml span-80, cross-linking agent was 10ml formaldehyde, phase ratio was 6:1, reaction temperature was 88℃ and stirring rate was 400r/min. The acetalation degree of beads was 30% and the amount of beads(diameter 0.30-0.45mm)accunted 80% .

关 键 词：疏水作用色谱 填料 PVA白球 球状交联聚乙烯醇颗粒 

分 类 号：TQ421.381[化学工程] TQ325.3