氨力农在慢性肺心病急性发作期的治疗作用  

The Therapentic Effect of Amrinone in the Treatment of Patients with Acute Exacerbation of Chronic Pulmonary Heart Disease

作　　者：罗艳蓉[1] 韩志青[1] 徐兆余[1] 李海玲[1] 

机构地区：[1]上海市杨浦区中心医院呼吸科,200090

出　　处：《医药导报》2002年第1期27-28,共2页Herald of Medicine

摘　　要：目的 :研究氨力农对慢性肺心病急性发作期患者的心功能、肺动脉压PAP的作用。方法 :将 34例慢性肺心病急性发作期患者随机分为两组 ,每组 17例 ,对照组给予常规治疗 ,治疗组在常规治疗的基础上给予氨力农 5～ 10mg·kg 1 治疗 ,疗程均为 7d。观察两组患者治疗前后心功能、PAP变化。结果 :治疗组心功能改善和PAP下降与对照组比较差异有显著性 ( P <0 .0 5 )。结论 :氨力农能明显改善慢性肺心病急性发作期患者的心功能和降低肺动脉高压。Objective:To study the effect of amrinone on the cardiac function and pulmonary arterial pressure (PAP) in patients with acute exacerbation of chronic pulmonary heart disease. Methods:34 patients with acute exacerbation of chronic pulmonary heart disease were randomly divided into two groups. On the basis of routine treatment, the 17 patients of the treatment group were given each 5～10 mg·kg 1 of amrinone, q.d., while the other 17 patients of the control group were subjected only to the routine treatment. The course of treatment in both groups lasted 7 days. The cardiac function and PAP of the patients in both groups were determined before and after the treatment. Results:Patients in the treatment group had a better improvement in cardiac function and a more marked decline in PAP, as compared with patients of the control group(P<0.05). Conclusion:Amrinone is capable of improving cardiac function and lowering PAP significantly in patients with acute exacerbation of chronic pulmonary heart disease.

关 键 词：氨力农 慢性肺心病 心功能 肺动脉压 急性发作期 治疗 

分 类 号：R541.5[医药卫生—心血管疾病] R972[医药卫生—内科学]