异丙托溴铵沙丁胺醇雾化吸入治疗肺炎  

Ipratropine Bromide and Salbutamol Nebulization as an Adjuvant Measure in the Treatment of Pneumonia

作　　者：郑敬阳[1] 陈志宏[1] 杨俭治[1] 朱振宏[1] 

机构地区：[1]福建省泉州市儿童医院哮喘防治中心,362000

出　　处：《医药导报》2002年第1期33-34,共2页Herald of Medicine

摘　　要：目的 :探讨异丙托溴铵、沙丁胺醇雾化吸入治疗支气管肺炎的疗效。方法 :支气管肺炎患儿 3 54例 ,在常规治疗的基础上 ,治疗组 1 99例给予 0 .0 2 5%异丙托溴铵 0 .5～ 1 .5mL、0 .5%沙丁胺醇 0 .2 5～ 0 .75mL酌情经压缩吸入机雾化吸入 ,对照组 1 55例常规抗感染治疗 ,比较两组症状、体征消失时间、住院时间 ,观察治疗组不良反应。结果 :治疗组住院时间及各症状、体征消失时间均比对照组短 ,两组比较差异有极显著性 (P <0 .0 1 ) ,其中退热时间两组比较差异无显著性 (P >0 .0 5) ,治疗组未出现明显副作用。结论 :异丙托溴铵、沙丁胺醇雾化吸入 ,能止咳化痰 ,缩短病程 ,较安全可靠。Objective:To probe into the therapeutic effectiveness of ipratropine bromide and salbutamol sulfate nebulization as an adjuvant measure in the treatment of bronchopneumonia. Methods:On the basis of routine treatment, 199 patients of the treatment group were given each additionally a daily nebulization of 0.025% ipratropine bromide 0.5～1.5 mL and salbutamol sulfate 0.25～ 0.75 mL throughout the period of hospitalijation. 155 patients of the control group were treated with the routine method only. The symptoms and signs including the time of disappearance of moist rales, as well as the duration of hospitalization in patients of the two groups were compared. Adverse reactions in patients of the treatment group were also noticed. Results:The curative effect of the treatment group was apparently better.The differences between the duration of hospitalization, time of diappearance of symptoms of the two groups were highly significant(P<0.01). The difference between the time of abatement of fever of the two groups, however, was not significant(P>0.05). No distinct side effects were seen in the treatment group. Conclusion:Ipratropine bromide and salbutamol sulfate nebulization was shown to have antitussive and expectorant effects. It could improve the patients' condition, shorten the course of illness. It is likely to be a safe and reliable adjuvant measure for the treatment of pneumonia.

关 键 词：异丙托溴铵 沙丁胺醇 肺炎 雾化吸入 治疗 

分 类 号：R563.1[医药卫生—呼吸系统] R974.3[医药卫生—内科学]