新型放射性^(32)P-血管支架的制备  

The preparation of a ^(32)P-radioactive stent

作　　者：张晓东[1] 李文新[1] 高东升[2] 李晴暖[1] 汪颖[1] 李宇国[1] 黄旋[1] 陈润芬[2] 黄定九[2] 

机构地区：[1]中国科学院上海原子核研究所放药中心,上海201800 [2]上海第二医科大学附属仁济医院心内科,上海200001

出　　处：《核技术》2002年第1期78-80,共3页Nuclear Techniques

基　　金：中国科学院上海浦东新区种子基金 (PKZ990 3)资助

摘　　要：In this work a new method was described to prepare 32 P-radioactive stents which was used to reduce the restenosis after PTCA. This new method included four steps: electroplating Ni film which can catalyze the chemical plating reaction; chemical plating Ni-( 32P)P film; electroplating Au film and heat treating on 620-640℃. The second step was most important. 32 P-calcium hypophosphite was adopted as the radioactive source. 22 of 32 P-stents with the radioactivity range from 0.3 to 1.4 were achieved successfully.In this work a new method was described to prepare 32 P-radioactive stents which was used to reduce the restenosis after PTCA. This new method included four steps: electroplating Ni film which can catalyze the chemical plating reaction; chemical plating Ni-( 32P)P film; electroplating Au film and heat treating on 620-640℃. The second step was most important. 32 P-calcium hypophosphite was adopted as the radioactive source. 22 of 32 P-stents with the radioactivity range from 0.3 to 1.4 were achieved successfully.

关 键 词：^32P 放射性支架 化学镀 次磷酸钙 磷32 血管支架 非晶态合金 镍磷镀层 腔内冠状动脉成形术 

分 类 号：R622.4[医药卫生—整形外科] R817.5[医药卫生—外科学]