生物膜色谱及其在药物活性成分分析中的应用  

Biomembrane Chromatography and Its Applications in the Analysis of Active Components of Drugs

作　　者：毛希琴[1] 孔亮[1] 汪海林[1] 邹汉法[1] 

机构地区：[1]中国科学院大连化学物理研究所国家色谱研究分析中心,大连116021

出　　处：《分析化学》2002年第2期231-236,共6页Chinese Journal of Analytical Chemistry

摘　　要：介绍了一种新兴的色谱技术──生物膜色谱技术，综述了生物膜色谱技术近十几年的发展状况、生物膜的制备与固定化的各种方法，着重介绍其用于药物与膜相互作用研究的原理及研究成果，并展望了该技术在药物活性成分筛选和活性评价领域的应用前景。A new chromatographic method-biomembrane chromatography is introduced. Its development in the last decade, methods for the preparation, immobilization of biomembrane stationary phase are reviewed focused on the principle of the interaction of biomembrane, drugs, achievement in the field. The application prospect of biomembrane chromatography in the field of screening active components from drugs, evaluating their bioactivity is highlighted.

关 键 词：生物膜 固定化 药物 活性成分 分析 生物膜色谱 相互作用 药物筛选 

分 类 号：O657.7[理学—分析化学]