皮肤非典型分枝杆菌感染组织病理学特征  

Histopathologic characteristics of atypical mycobacterium infection of the skin

作　　者：余力[1] 肖莎[1] 

机构地区：[1]第一军医大学珠江医院病理科,广州510282

出　　处：《诊断病理学杂志》2002年第1期15-16,T003,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的　探讨皮肤非典型分枝杆菌感染 (AMI)的组织病理学特征。方法　对 8例皮肤AMI的活检标本进行病理组织学观察与分析。结果　皮肤AMI典型的组织学特点是类结核肉芽肿性炎 ,肉芽肿外形不规则 ,可见窦隙样腔隙形成 ,内有红染较致密坏死样物 ,边缘见有较多的泡沫细胞 ,周边上皮样细胞无明显栅栏状排列 ,浸润细胞以淋巴细胞为主。结论　皮肤AMI病理组织学改变不尽一致 ,但均有类似的病理学改变 ,如皮损有窦道形成 ;肉芽肿形态不规则 ,可见窦样红染均质坏死物 ,内有漂浮细胞 ;交界处无明显的栅栏状结构 ,可见较多泡沫样细胞。Objective To investigate the histopathologic characteristics of atypical mycobacterium infection (AMI) of the skin. Methods The histologic changes were observed under microscope in 8 cases of AMI of the skin. Results The histologic features of AMI included tuberculoid granulomas that were lack typical cheese-like necrosis. The lesion was irregular in shape, surrounded by foamy cells and epithelioid cells without fences-like arrangement. The sinus-like lacuna filled with dense, red stained necrotic materials and floated with metamorphic cells were found in the lesion. Lymphocyte was the predominant inflammatory cells. Conclusions Histopathological changes of AMI of the skin are heterogeneous, but there are certain features commonly existed: i.e. irregular tuberculoid granuloma, sinus-like lacuna formation and pink homogeneous material. The final diagnosis of AMI depends on the pathogenic analysis.

关 键 词：非典型分枝杆菌 病理组织学 皮肤感染 AMI 

分 类 号：R754[医药卫生—皮肤病学与性病学]