头低位卧床对人EEG的影响  

Effect of Head down Bed Rest on Human EEG

作　　者：韩东旭[1] 刘月红[1] 周传岱[1] 张宝兰[1] 费锦学[1] 刘钢[1] 

机构地区：[1]北京航天医学工程研究所,北京100094

出　　处：《航天医学与医学工程》2001年第3期168-171,共4页Space Medicine & Medical Engineering

摘　　要：目的探讨短期 - 6°头低位卧床模拟失重对人脑EEG的影响。方法记录 1 2名 1 8～ 2 2岁健康男性卧床前、卧床期间 (第 3、4、6天 )及恢复期 (第 3天 )清醒闭眼安静状态的 1 6导EEG ,进行功谱分析。结果卧床期间 ,EEG峰值频率逐渐慢化 (第 6天 ,P <0 .0 5) ,α段活动增强 (α1 :P <0 .0 0 1 ;α2 :第 3、6天 ,P<0 .0 5;第 4天 ,P <0 .0 0 1 ) ,第 4天最显著 ,α1 /α2 上升 (第 6天 ,C3、C4:P <0 .0 2 ;F4、P4、T3、T4、T5:P <0 .0 5) ;θ活动增强 (P <0 .0 0 1 ) ,额区第 3天最显著 ,枕顶区第 4天最显著 ,同时θ/α明显上升 (第 6天 ,P3、O1 :P <0 .0 5) ;此外 ,β1 活动也显著增强 (P <0 .0 0 1 ) ,第 3天最明显。卧床结束后 3dEEG峰值频率已恢复至实验前水平 ,其余指标尚在恢复中。结论头低位卧床导致人脑EEG频谱结构及活动强度明显改变 。Objective To study the influences of short term simulated weightlessness on human EEG. Method EEG of 12 male subjects(aged 18～22) was recorded, pre HDBR(-6°head down bed rest), mid HDBR (3rd,4th,6th day) and post HDBR (3rd day). Then these EEG recordings were analyzed by power spectral analysis. Result During HDBR, peak frequency of EEG gradually slowed down (6th day, P<0.05). α band activities were enhanced(α 1:P<0.001. α 2:3rd and 6th day, P<0.05; 4th day, P<0.001), and reached maximum on the 4th day. α 1/α 2 ascended(6th day, C 3 and C 4:P<0.02; F 4,P 4,T 3,T 4,T 5:P<0.05). θ band activities enhanced(P<0.001), and reached maximum on the 3rd day at frontal regions, on the 4th day at parieto occipital regions.θ/α ascended obviously (6th day, P 3,O 1:P<0.05). Meanwhile,β 1 activities also enhanced(P<0.001), and reached maximum on the 3rd day at frontal regions. After HDBR, the index that recovered to the pre HDBR level first was EEG peak frequency. Conclusion HDBR caused obvious changes of EEG power spectrum characteristic. There exists a potential influence on brain function.

关 键 词：模拟失重 头低位倾斜 卧床实验 脑电图 

分 类 号：R852.22[医药卫生—航空、航天与航海医学] R741.044[医药卫生—临床医学]