不同蛋白含量饮食对糖尿病大鼠肾组织核酸含量的影响  

Effects of Dietary Protein Intake on Nucleic Acid Content of Kidney in Streptozotocin-Induced Diabetic Rats

作　　者：蒋更如[1] 左静南[1] 侯积寿[1] 熊祖应 刘秀英[1] 宋小君[1] 

机构地区：[1]上海第二医科大学附属新华医院内科

出　　处：《上海第二医科大学学报》1991年第2期137-139,共3页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：将糖尿病鼠随机分成三组,分别饲以7%,20%和40%的蛋白质饮食一个月,结果发现7%组肾组织内核酸含量及RNA/DNA比率明显降低,而40%组则明显增加。提示蛋白质摄入量可以影响糖尿病大鼠肾组织内核酸的代谢,从而影响肾脏结构和功能。Streptozocin-induced diabetic rats were randomly divided into three groups and fed respectively with diets containing 7%, 20%, 40% protein. Decreased nucleic acid content and RNA/DNA ratio in the kidney were found in diabetic rats fed with low protein diet (7%) as compared with those normal protein (20%). In contrast, nucleic acid content and RNA/DNA ratio were increased in the group of animals fed with 400% protein diet. These results suggest that dietary protein intake may influence nucleic acid metabolism of the kidney in diabetic rats.

关 键 词：糖尿病 核酸 尿蛋白 肾 

分 类 号：R587.102[医药卫生—内分泌]