肝炎患者血浆组织纤溶酶原激活剂及其抑制剂的变化  

Study on Changes of Tissue Plasminogen Activator and It's Inhibitor in Patients with Viral Hepatitis

作　　者：王学峰[1] 邵慧珍[1] 王鸿利[2] 吴瑞庭[3] 姜嘉[3] 沈霖德[3] 巫善明[3] 孙家强[3] 

机构地区：[1]上海第二医科大学附属瑞金医院检验科 [2]上海血液学研究所 [3]上海市传染病医院

出　　处：《上海第二医科大学学报》1991年第3期249-251,共3页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：作者报道39名正常人及200例各型病毒性肝炎患者的血浆组织纤溶酶原激活剂(t-PA)和纤溶酶原激活剂抑制剂(PAI)的测定结果:正常人组t-PA和PAI分别为1.92±0.72IU/ml和6.38±2.57AU/ml;各型肝炎组的t-PA活性较正常人组高(P<0.001),PAI活性较正常人组低(P<0.001)两者均随病情的严重程度变化。Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI) were measured in 39 normal persons and 200 patients with various form of viral hepatitis. The results showed that the normal plasmic level of t-PA and PAI was 1.97±0.72 IU/ml and 6.38±2.57 AU/ml respectively, and the activity of t-PA was significantly raised in patient's group but PAI was lower than in controls. The changes of t-PA and PAI was related to the severity of viral hepatitis.

关 键 词：病毒性肝炎 T-PA PAI 血浆 诊断 

分 类 号：R512.604[医药卫生—内科学]