糖尿病肾病患者血浆t-PA、PAI变化的初步观察  

Changes of Plasma t-PA,PAI in Diabetic Patients

作　　者：周同[1] 董德长[1] 钱萍[1] 姚建[1] 王鸿利[2] 邵慧珍[2] 王学峰[2] 

机构地区：[1]上海第二医科大学附属瑞金医院内科 [2]上海血液学研究所

出　　处：《上海第二医科大学学报》1991年第4期322-324,共3页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：检测25例糖尿病肾病患者血浆组织纤溶酶原激活物抗原(t-PA:Ag)和活性(t-PA:A)、纤溶酶原激活抑制物活性(PAI:A)以及血管性假血友病因子抗原(VWF:Ag)。结果表明,患者的t-PA:Ag低于正常,PAI:A,VWF:Ag高于正常,提示尿蛋白增多的糖尿病患者纤溶活性减低并可能伴血检形成。Plasma t-PA:Ag, T-PA:A, PAI:A and VWF were detected in 25 cases of diabetes. The results showed that t-PA:Ag, t-PA:A were lower than mormal and PAI:A was higher than mormal control. VWF:Ag was also elevated. This indicates that fibrinolysis increases when excretion of urinary albumin is increased in diabetes. This change may indicate the possibility of thromosis.

关 键 词：糖尿病肾病 纤溶酶原 T-PA PAI 

分 类 号：R587.1[医药卫生—内分泌]