哺乳动物及人精子的Ca^(2+)通道与顶体反应  

Calcium Channels and Acrosome Reaction in Sperm of Mammalian and Human

作　　者：张习春[1] 肖杭[1] 

机构地区：[1]南京医科大学应用毒理研究所神经毒理室,南京210029

出　　处：《生殖与避孕》2001年第6期330-335,共6页Reproduction and Contraception

基　　金：国家自然科学基金 (3 0 170 811)资助课题

摘　　要：在精子生理活动中 ,Ca2 +通道起重要作用。近年来 ,随着荧光探针 ,分子生物学以及电生理技术的飞速发展 ,人们更明确地认识到 Ca2 +通道的重要性 ,特别是在顶体反应中的作用 ,并对其功能性亚单位有了一定的了解。在参与精子顶体反应的众多 Ca2 +通道中 ,电压依赖性 Ca2 +通道倍受重视。同时 。Ca 2+ channels play an important role in sperm physiology. In recent years, with the rapid development of fluorescent probes, molecular biology and electrophysiological technique, the important status of Ca 2+ channel, especially in triggering the sperm AR, is further understood. Meanwhile, some knowledge of the functional subunits of Ca 2+ channel has been also attained. The roles of the voltage dependent calcium channels are more concerned among all the Ca 2+ channels correlating to the sperm AR. These studies provide us with new perspective to the treatment of male infertility and the practice of male contraception.

关 键 词：精子 CA^2+通道 顶体反应 哺乳动物 

分 类 号：R321[医药卫生—人体解剖和组织胚胎学]