氯硝柳胺配伍剂抑制钉螺上爬作用的研究  

Climbing-upward Inhibition of Oncomelania hupensis by Niclosamide Combination

作　　者：朱丹[1] 谢法仙[1] 鲍子平[1] 朱达培[1] 倪传华[1] 

机构地区：[1]中国预防医学科学院寄生虫病研究所

出　　处：《中国寄生虫学与寄生虫病杂志》2001年第6期348-350,共3页Chinese Journal of Parasitology and Parasitic Diseases

基　　金："九五"国家科技攻关资助课题 (No .96 90 6 0 4 0 5 )~~

摘　　要：目的　研究氯硝柳胺与杀虫丁配伍的杀螺效果及抑制钉螺上爬作用。方法　采用实验室喷洒及浸杀方法观察氯硝柳胺和杀虫丁配伍的杀螺效果和抑制钉螺上爬作用。结果　氯硝柳胺 0 .2mg/L配伍杀虫丁0 .1mg/L浸杀钉螺效果较好 ,其LC90 为 0 .198mg/L ,抑制钉螺上爬达 92 .6 7% ,与氯硝柳胺单剂杀螺效果 (LC90 为0 .2 0 7mg/L)无显著性差异。 结论　筛选出的氯硝柳胺与杀虫丁配伍剂能有效抑制钉螺上爬 ,提高杀螺效果 。Objective To develop a combination of molluscicide/insecticide with a good molluscicidal effect, especially an inhibitory effect on climbing upward of Oncomelania hupensis . Methods Experiments on molluscicidal and snail climbing inhibition effect of the combination of niclosamide and shachongding [(dimethylamine) trithacyclohexane hydrochloride] were conducted by immersion and spraying in laboratory. Results The combination of niclosamide (0.2 mg/L) and shachongding (0.1 mg/L) showed an inhibition of 92.67% of snails to climb up. There was no significant difference in molluscicidal effect between the combination (LC 90 0.198 mg/L) and niclosamide alone (LC 90 0.207 mg/L). Conclusion The combination showed an effective inhibition on the climbing upward of snails in water so as to improve the molluscicidal effect and reduce the cost of mollusciciding.

关 键 词：氯硝柳胺 杀虫丁 杀螺剂 配伍剂 钉螺 血吸虫病 疾病预防 

分 类 号：R978.63[医药卫生—药品] R532.21[医药卫生—药学]