原发性甲状旁腺功能亢进症的临床特点及治疗  

Clinical research of primary hyperparathyroidism

作　　者：徐少明[1] 王平[1] 郑毅雄[1] 虞志刚[1] 陈健[1] 

机构地区：[1]浙江大学医学院附属第二医院普通外科,杭州310009

出　　处：《中华医学杂志》2001年第23期1453-1455,共3页National Medical Journal of China

摘　　要：目的　探讨我国原发性甲状旁腺功能亢进症 (PHPT)的临床特点和手术治疗方法。方法　分析 1 968～ 2 0 0 1年间收治的 2 8例PHPT患者的临床资料并与国内相关文献进行比较分析。结果　手术治疗 2 8例 ,颈部探查术 1 2例 ,囊肿切除术 1例 ,癌根治术 1例 ,甲状旁腺腺瘤直接切除术 1 4例。术后病理证实 ,甲状旁腺腺瘤 2 5例、甲状旁腺腺癌 2例、甲状旁腺囊肿 1例。 2 8例PHPT患者全部治愈 ,肿瘤无复发。结论　在我国PHPT临床上比较少见 ,一般好发于 3 0～ 4 0岁的青壮年 ,有骨病者占 90 %以上。单个甲状旁腺腺瘤可在颈小切口下直接行甲状旁腺腺瘤切除术 ,效果优于常规颈探查术。Objective To investigate the clinical features and therapeutic procedures of primary hyperparathyroidism(PHPT) in China. Methods Clinical data of twenty eight consecutive in patients with PHPT hospitalized in the Second Hospital Affiliated to Zhejiang Universty Medical School during the period 1968～2001 were analyzed retrospectively and compared with the domestic relevant literature. Results Twenty eight patients underwent operative treatment, including exploratory operation of neck in 14 cases, cystectomy in one case, cancer radical operation in one case, and direct parathyroid adenomectomy in 14 cases with solitary adenoma. All cases resulted in normocalcemia after operation. The cure rate of PHPT was 100%. No early and long term operative complications and recurrence were found. Conclusion PHPT, mostly occuring among people aged 30～40, is rare in China. Osteopathy can be seen in 90% of PHPT patients. For solitary parathyroid adenoma, direct adenomectomy through small neck incision is a safe and effective alternative to conventional neck exploratory operation.

关 键 词：甲状旁腺功能亢进症 PHPT 外科手术 首发症状 诊断 

分 类 号：R653[医药卫生—外科学]