离子色谱法测定葡萄糖酸钙中的草酸根  

DETERMINATION OF OXALATE IN CALCIUM GLUCONATE BY ION CHROMATOGRAPHY

作　　者：徐继明[1] 嵇鸣[1] 颜茂珠[1] 

机构地区：[1]淮阴师范学院化学系,223001

出　　处：《化学分析计量》2001年第6期15-16,共2页Chemical Analysis And Meterage

摘　　要：利用单柱离子色谱系统,以NaHCO_3-Na_2CO_3溶液为流动相,对葡萄糖酸钙中的草酸根进行分离,并用电导检测法测定了葡萄糖酸钙中草酸根的含量。线性回归方程为y=1.147x+1.568,相关系数r=0.984,线性范围为0.01～30.00mg/L,以3倍信噪比计算,草酸根的检出限为13.2μg/L,回收率为96％～105％。Oxalate in calcium gluconate was separated with sodium bicarbonate and carbonate as eluent by anion - exchange chroma-tography and the oxalate content is determined with conductivity detection. The regression equation is y=1. 147x+1.568, the correlative coefficient is r = 0.984, the linear range is 0.01 - 30.00 mg/L. Calculating at three times of the signal - noise ratio, the detection limit of oxalate is 13.2 μg/L, the recovery rate is 96% - 105%.

关 键 词：离子色谱法 葡萄糖酸钙 草酸根 测定 补钙制品 分析 

分 类 号：R977.5[医药卫生—药品] TQ464.9[医药卫生—药学]