烟酸铬对四氧嘧啶性糖尿病小鼠肝糖原含量的影响  

Effects of Chromium Nicotinate on the content of liver starch of diabetic mice induced by alloxan

作　　者：李善花[1] 金政[1] 朴丽花[1] 李相伍[1] 

机构地区：[1]延边大学医学院组织学与胚胎学教研室,延吉133000

出　　处：《微量元素与健康研究》2001年第4期5-6,共2页Studies of Trace Elements and Health

摘　　要：目的 :观察用烟酸铬处理四氧嘧啶性糖尿病小鼠 4周后肝糖原含量的变化。方法 :将糖尿病小鼠随机分为三个组 :糖尿病对照组、实验 组 (烟酸铬 Cr3 + 2 5 0 μg/kg·d)、实验 组 (烟酸铬 Cr3 + 1 2 5 μg/kg·d) ,另设正常对照组 ,做过碘酸雪夫氏 (PAS)反应显示肝糖原。结果 :实验组与糖尿病对照组相比 ,肝细胞糖原含量增多。结论 :烟酸铬能够增加肝糖原的含量 。AIM:It was observed the change of Chromium Nicotinate on the content of liver starch of diabetic mice induced by alloxan 4 weeks later.METHODS:The diabetic mice were divided randomly into 3 groups:diabetic control group,experimental group Ⅰ(Chromium Nicotinate Cr 3+ 250 μg/kg·d),experimental group Ⅱ(Chromium Nicotinate Cr 3+ 125 μg/kg·d),in addition,normal control group was set,with the reaction of PAS,displayed liver starch.RESULTS: Compared experimental group with diabetic control group,content of liver starch was increased.CNCLUSION:Chromium Nicotinate could increase the content of liver starch and facilitate glucose utilization of peripheral tissue.

关 键 词：铬 四氧嘧啶性糖尿病 组织化学 小鼠 烟酸铬 肝糖原 

分 类 号：R587.1[医药卫生—内分泌] Q581[医药卫生—内科学]