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作 者:唐非[1] 张水兵[1] 谷康定[1] 汪亚州[1] 运珞珈[1] 张金荣[1]
机构地区:[1]华中科技大学同济医学院环境医学研究所,武汉430030
出 处:《同济医科大学学报》2001年第6期541-543,共3页Acta Universitatis Medicinae Tongji
基 金:国家"九五"重点科技攻关计划项目 (No.96 - 911- 0 7- 0 2 -0 2 )
摘 要:应用大孔树脂吸附浓集水中有机物的技术 ,结合 Ames致突变试验 ,研究了不同水文期的东湖与汉江水源水及其所制成的自来水中非挥发性有机物的致突变性。结果发现 :在加与不加体外代谢活化系统 (S9)的条件下 ,除枯水期外 ,其他水文时期东湖与汉江水源水中非挥发性有机物对 TA98菌株的致突变试验为阳性结果 ;各水文期东湖与汉江自来水中有机物对 TA98和 TA10 0菌株均具有致突变性 ,且致突变比活性强度均明显高于水源水 ,各期水样致突变比活性强度由强至弱依次为平水期 >枯水期 >丰水期。Water samples from raw and tap water derived from these suface sources were collected separately at Donghu lake and Hanjiang river of Wuhan in average, high and low flow period during a water year. The nonvolatile organic compounds (NOCs) in water were concentrated on XAD 2 resin and the mutagenicity of such NOCs were examined by using the Salmonella mutagenicity test (Ames test). The direct and indirect mutangenicity of NOCs in the raw watr, except low flow period, was observed in the presence or absence of S. typhimurium TA98. The mutagenicity of NOCs in all the tap water samples was detectable by means of TA98 and TA100 in the presence or absence of S9 mix, obviously higher than in the raw water. Comparative analysis of NOCs in water for mutagenicity showed a consistent pattern of mutagenic potency at different hydrographic periods, with decreasing activity in the order of average> low>high flow period.
分 类 号:R123[医药卫生—环境卫生学] R994.6[医药卫生—公共卫生与预防医学]
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