肺减容术治疗重度阻塞性肺气肿的临床研究  

Clinical evaluation of the lung volume reduction surgery(LVRS) in severe obstruction emphysema;

作　　者：于云芝[1] 肖邦榕[1] 格桑耕噶[1] 丛伟[1] 

机构地区：[1]四川省人民医院,四川成都610072

出　　处：《四川医学》2002年第2期165-166,共2页Sichuan Medical Journal

摘　　要：目的　研究肺减容手术 (LVRS)对重度慢性阻塞性肺气肿患者肺功能等临床指标及生存质量的影响。方法　对 15例重度阻塞性肺气肿患者施行LVRS ,并于LVRS后随访 2 4个月 ,分别于手术后 6、12及 2 4个月测定有关临床指标 :肺功能、血气分析、6分钟步行距离 ( 6MWD)。结果　术后 6,12及 2 4月与术前比较 ,1秒钟用力呼气容积 (FEV1)显著增加 (P <0 .0 1) ,肺总量 (TLC)、残气容积 (RV )、残总比 (RV/TLC)均明显降低 (P <0 .0 1) ,6MWD增加 (P <0 .0 5 ,P <0 .0 1)。日常生活活动及社会生活能力评分均提高 (P <0 .0 5 ,P <0 .0 1)。结论　LVRS能明显改善重度阻塞性肺气肿患者的肺功能及PaO2 等临床指标 。Objective To evaluate the clinical benefit provided by lung volume reduction surgery(LVRS) in severe obstruction emphysema.Methods Post visits in succeeding 24 months of 15 patients with severe emphysema after LVRS and the following clinical indices were measured at the 6 th ,12 th ,24 th month after the operation were carried out:lung function,blood gas analysis and walking distance in 6 minutes(6MWD).Results Compared with the data of pre operation of FEV 1and the data of post operation at the 6 th ,12 th and 24 th increased( P < 0.01 ),TLC?RV?RV/TLC decreased( P < 0.01 ),and 6MWD increased( P <0.05, P <0.01).The evaluation results on both daily living activities and social association capability increased( P <0.05, P <0.01).Conclusion The present study should be that the LVRS may sigificant improve the clinical indices including lung function?PaCO 2as well as the quality of life in severe emphysema.

关 键 词：阻塞性肺气肿 肺减容术 生活质量 治疗 临床研究 

分 类 号：R655.3[医药卫生—外科学]