1958～1997年湖南A铀矿矿工死亡原因的流行病学调查  

STUDY ON MORTALITY OF A COHORT OF MINERS IN A CHINESE URANIUM MINE DURING 1958～1997

作　　者：温晋爱[1] 姜如意[1] 常学奇[1] 钟锐[1] 谷娟娟[1] 王武安 张德江 张岩波[3] 

机构地区：[1]中国辐射防护研究院,太原030006 [2]湖南A矿 [3]山西医科大学,太原030012

出　　处：《辐射防护》2002年第1期44-50,共7页Radiation Protection

摘　　要：为了对我国铀矿工死亡原因进行综合分析 ,特别是对肺癌死亡的剂量 -效应关系进行深入的探讨 ,采用历史前瞻性方法 ,对湖南 A铀矿矿工进行了辐射流行病学调查。结果显示 ,肺癌的标准化死亡比 (SMR )显著升高 ,其与氡子体累积暴露量之间的趋势检验具有统计学显著性 ,说明该矿矿工肺癌的超额死亡与氡子体累积暴露量有关 ,这一结论与世界其它国家的同类研究的结果是一致的。该矿矿工肺癌的超额相对危险 (ERR )系数为 2 .0 8% / WLM,其在 BEIR 报告 (1.5± 1.2 ) % / WL M的范围内。本调查截至 1997年底 ,存活者的平均年龄只有 5 1岁 ,为了进一步观察辐射致癌危险随时间的变化 。The main purpose of this paper is to evaluate the death of Chinese uranium miners, especially to study the exposure response relationship of lung cancer. The retro prospective epidemiologic study were adopted for uranium miners of an uranium mine in Hunan province. The result shows that a statistically significant excess of SMR has been observed for lung cancer death and the trend test shows a statistically significant trend for the risk of lung cancer death as a function of cumulative radon exposure. It manifested that the excess death of lung cancer of uranium miners is correlated with the cumulative radon exposure. The coefficient of excess relative risk (ERR) is 2.08% per WLM (Working Level Month) and in the range of the evaluation of the'BEIR Ⅳ'report of the U.S. National Academy of Science. Because the mean age of alive uranium miners was only 51 years old until the end of 1997, the follow up and study on this cohort will be continued in the future in order to observe the change of radiogenic risk with time. (

关 键 词：流行病学调查 矿工 肺癌 铀矿 剂量-效应关系 氡子体 氡 职业照射 辐射剂量 辐射危害 

分 类 号：R181.3[医药卫生—流行病学]