反相高效液相色谱法测定利凡诺氧化锌油中利凡诺的含量  

Determination of steril in steril and zinc oxide oil by RP-HPLC

作　　者：郑峰[1] 程民[1] 朱建永[1] 

机构地区：[1]安徽省淮北市药品检验所,淮北235000

出　　处：《安徽医药》2001年第4期300-302,共3页Anhui Medical and Pharmaceutical Journal

摘　　要：目的　应用反相高效液相色谱法 (RP HPLC)测定利凡诺氧化锌油中利凡诺的含量。方法　色谱柱 :DimkaLunaC18柱 ;流动相 :甲醇 乙腈 水 (6 0∶37∶3) ;检测波长 :2 6 9nm ;流速 :1 0ml·min-1。结果　利凡诺在 15 4～ 35 8μg·L-1浓度范围内线性关系良好 ,平均回收率为 99 30 % ,RSD为 0 36 %。结论　本法简便、快速、灵敏、准确。AIM Steril was determined by RP HPLC in steril and zinc oxide oil. METHODS The column: Dimka Luna C 18 column; The mobile phase: methanol acetonitrile water (60∶37∶3); The detection wave length: 269 nm; The flow rate: 1 0 ml·min -1 . RESULTS The calibration curve was linear in the range of 15 4～35 8 μg·ml -1 , The average recovery was 99 30%(RSD=0 36%). CONCLUSION This method is simple, rapid, sensitive and accurate.

关 键 词：利凡诺氧化锌油 利凡诺 反相高效液想象以谱法 药物含量测定 

分 类 号：R927.2[医药卫生—药学]