鼠胚胎干细胞体外分化的单个心肌细胞获取方法  

The method to get single cardiomyocyte from embryonic stem cells differentiated in vitro

作　　者：范云[1] 张建保[2] 菅中[2] 龙开平[2] 徐传镶[1] 

机构地区：[1]西安交通大学绝缘研究所,陕西西安710049 [2]第四军医大学物理学教研室

出　　处：《心脏杂志》2001年第5期379-380,共2页Chinese Heart Journal

基　　金：国家自然科学基金资助项目 ( No.1990 2 0 2 0 )

摘　　要：用鼠胚胎干细胞在体外分化成心肌细胞是研究心肌细胞进化和生理学实验的新途径 ,胚胎干细胞最初是从鼠胚胎在胚泡阶段或 8个细胞的胚胎阶段的内部没分化的细胞中得到。其可以定向诱导分化为几乎所有种类的细胞 ,此文介绍了由鼠胚胎干细胞分化成为心肌细胞及单个心肌细胞的获取方法。A new approach to study cardiomyogenesis is provided by the use of pluripotent murine embryonic stem cells differentiated in vitro.The embryonic stem cells originally have been derived from undifferentiated cells of the inner cell mass of murine embryos at blastocyst stage or from eight-cell embryos. They have been shown to differentiate into all kinds of different cells. In this paper a method how to get single cardiomyocyte from embryonic stem cells differentiated in vitro has been introduced.

关 键 词：胚胎干细胞 心肌细胞 分化 体外 

分 类 号：Q813.1[生物学—生物工程]