124例尘肺结核化疗疗效观察  

Clinical observation of chemotherapeutic effect in 124 cases of pneumoconiosis tuberculosis

作　　者：余中英[1] 刘耀松[1] 王文炳[1] 朱长鸣[1] 

机构地区：[1]大冶有色金属公司总医院呼吸内科,黄石435005

出　　处：《中国防痨杂志》2001年第4期228-230,共3页Chinese Journal of Antituberculosis

摘　　要：目的　探讨尘肺结核菌阳患者使用不同疗程化疗的近远期疗效。方法　观察 10年间的菌阳尘肺结核 12 4例化疗效果。按不同疗程分为 12月组 ( 3HRZS/ 9HRE)、18月组 ( 3HRZS/ 6HRZ/9HRE)、2 4月组 ( 3HRZS/ 9HRZ/ 12HRE)方案 ,全程督导治疗结束随访 5年。考核标准以痰菌为主。结果　 12月组、18月组、2 4月组方案化疗结束痰菌阴转率达到 99.2 % ,随访期间痰菌复阳率分别为 17.4 %、3.8%、1.4 %。结论　对 18月组、2 4月组方案的远期疗效满意。 18月组方案适用于Ⅰ～Ⅱ期尘肺结核 ,2 4月组方案适用于Ⅲ期尘肺结核。Objective To assess the therapeutic efficacy of chemotherapy with varied course on culture positive pneumoconio tuberculosis cases.Methods To observe the therapeutic effect in 124 patients with culture positive pneumoconio tuberculosis in 10 years.According to chemotherapy duration,patients were divided into 12 month group (3HRZS/9HRE),18 month group (3HRZS/6HRZ/9HRE) and 24 month group (3HRZS/6HRZ/12HRE).All patients who completed the therapy were followed up for 5 years.Evaluating the therapeutic effect depended on sputum bacteriological conversion.Results Sputum negative conversion rates of 3 groups at the end chemotherapy were all 99.2%,and their recurrent rates in follow up period were 17.4%,3.8%,and 1.4% respectively.Conclusion 12 month regimen is suitable for phrase Ⅰ～Ⅱ pneumoconio tuberculosis,24 month regimen is suitable for phrase Ⅲ pneumoconio tuberculosis.

关 键 词：药物疗法 尘肺结核 肺结核 化疗 疗效 病例报告 

分 类 号：R521[医药卫生—内科学]