退行性瓣膜病主动脉瓣返流时冠脉血流及冠脉血流储备的研究  

Effect of Degenerate Valvular Regurgitation Disease on Coronary Flow Reserve

作　　者：丁萍[1] 童鸿[1] 徐晓文[1] 陈婉斐 

机构地区：[1]浙江省台州市中心医院,浙江台州318000

出　　处：《中国医学影像技术》2002年第1期44-45,共2页Chinese Journal of Medical Imaging Technology

摘　　要：目的　应用多平面经食管超声心动图探讨退行性主动脉瓣在返流时对冠脉血流及冠脉血流储备 (CFR)的影响。方法　对主动脉瓣返流组 (轻度 2 0例、中度 15例 )及正常对照组 2 0例静脉注射潘生丁 ,分别测量静息状态 (rest)及注射潘生丁后 (DPM )冠脉血流频谱 ,舒张期峰值流速 (PDV)、平均流速 (MDV)、流速积分 (DVI) ;记录心率 (HR ) ;用药后 (应激状态 )与用药前 (静息状态 )测值之比 (D/R)即为CFR。结果　随返流程度的增加 ,PDV、MDV、VI及D/R比值均逐渐降低。组间有明显差异。结论　随返流程度的加重 ,冠脉血供逐渐减少 ,冠脉血流储备均逐渐降低。Objective To evaluate the effect of degenerate valvular regurgitation disease on the coronary flowing and coronary flowing reserve (CFR) with multiplane TEE. Methods In 35 patients with degenerate valvular regurgitation disease and 20 normal cases, multiplane TEE examination was performed to obtain coronary flow velocity (CFV),coronary flow frequence spectrum,heart rate (HR),diastolic peak flow velocity (PVD),mean flow velocity (MDV),flow velocity integral (DVI) in rest and after dipyridamole injected. Results The PDV,MDV,DVI and CFR decreased significantly in patient with degenerate valvular regurgitation disease. Conclusion Effect of degenerate valvular regurgitation disease on CFR is significant.

关 键 词：超声心动图 冠脉血流储备 退行性瓣膜返流疾病 心血管疾病 

分 类 号：R540.45[医药卫生—心血管疾病] R540.47[医药卫生—内科学]