5-甲基-2-氨基-1,3,4-噻二唑的合成  

Synthesis of 2-Amino-5-methyl-1,3,4-thiodiazole

作　　者：乐长高[1] 康文[1] 李光军[1] 邹小红 

机构地区：[1]华东地质学院应用化学系,临川344000 [2]江西临川市环保局环保监测站,临川344000

出　　处：《染料工业》2001年第4期29-30,共2页Dyestuff Industry

摘　　要：本文报道了用硫代氨基脲与乙酸在盐酸、磷酸、多聚磷酸、硫酸等催化下,合成5-甲基-2-氨基-1,3,4-噻二唑,并对工艺条件进行了试验,结果表明,最佳工艺条件为硫代氨基脲与乙酸的摩尔比为1:14,浓盐酸催化,回流3小时,产率为74.34％。2 - Ammo - 5 - methyl -1,3,4- thiodiazole was synthesized from aminothiourea and acetic acid in the presence of either hydrochloric acid or phosphoric acid or polyphosphoric acid or sulphuric acid as catalyst. The optimum conditions were found to be; molecular ratio of aminothiourea to acetic acid was 1:1.4; reflux time 3h.; hydrochloric acid being the catalyst. The yield was 74.34%.

关 键 词：1 3 4-噻二唑 催化剂 硫代氨基脲 重氮染料 中间体 5-甲基-2-氨基 

分 类 号：TQ612[化学工程—精细化工]