面刺凝胶中3种成分的含量测定  

Determination of the Contents of Three Ingredients in Comedo Gel

作　　者：罗东[1] 熊雄[1] 陈莉敏[1] 陈晓兰[1] 

机构地区：[1]第三军医大学西南医院药剂科,重庆市400038

出　　处：《中国药房》2002年第1期46-47,共2页China Pharmacy

摘　　要：目的 :建立面刺凝胶中安体舒通、氯霉素、甲硝唑的含量测定方法。方法 :采用多波长系数法测定3主药的含量 ,测定波长分别为239 0、276 0、313 5nm。结果 :平均回收率分别为 :安体舒通99 5 %(RSD为3 02 %) ;氯霉素101 61 %(RSD为1 47 %) ;甲硝唑101 47 %(RSD为2 00 %)。结论 :该方法简便、快速、准确 ,适用于多组分制剂的分析。OBJECTIVE:To establish a method for determining the contents of spironolactone chloramphenicol and metromidazole in Mianchi gel.METHODS:The concentrations of three main ingredients were determined by multiwavelengh coefficient spectrophotometry,the detecting wavelenghs being 239.0nm,276.0nm and 313.5nm respectively.RESULTS:The average recoveries and RSDs(n=5)were:spironolactone 99.5%,RSD=3.02%,chloramphenicol 101.61%,RSD=1.47%,metromidazole 101.47%,RSD=2.00%.CONCLUSION:This method is simple,rapid and accurate.It is good for determination of multicomponent preparation.

关 键 词：凝胶 多波长系数法 含量 测定 

分 类 号：R927.2[医药卫生—药学]