自身抗体与复发性流产的关系  

The relationship between some autoantibodies and recurrent spontaneous abortion

作　　者：毛立群[1] 李瑞民[2] 闫燕华[3] 

机构地区：[1]武警医学院微生物与免疫教研室,天津300162 [2]承德医学院微生物教研室,河北承德067000 [3]天津医科大学免疫教研室,天津300070

出　　处：《河北医学》2001年第12期1077-1079,共3页Hebei Medicine

摘　　要：目的 :探讨自身抗体与复发性流产的关系。方法 :采用酶联免疫吸附法 (ELISA)对 30例不明原因的复发性流产 (URSA)患者进行抗心磷脂抗体 (ACA)和抗血小板抗体 (PA)的检测 ,并与正常人进行比较。结果 :URSA组ACA～IgG、ACA～IgM或和PA～IgG的阳性率分别为 4 3.33%、30 .0 0 %和36 .6 7% ,与正常对照组相比有显著性差异。结论 :这些自身抗体的出现可能与流产有关。Objective: To study on relationships between some autoantibobies and recurrent spontaneous abortion. Method: Anticardiolipin antibody (ACA) and platelet associated immunoglobulin (PA ) was measured by enzyme linked Immunosorbent assay (ELISA) inperipheral blood of 30 women with unexplained recurrent spontaneous abortion(URSA). Results: The percents of ACA-IgG, ACA-IgM and PA-TgG among women with URSA were 43.33%, 30.00% and 36.67%. Compared with those in the normal control, they were increased (P<0.01, P<0.01, P<0.05). Conclusion: The increasing of ACA-IgG,ACA-IgM and PA-IgG may be associated with the occurrence of URSA.

关 键 词：复发性流产 抗心磷脂抗体 抗血小板抗体 流产 自身抗体 

分 类 号：R714.21[医药卫生—妇产科学]