老年戊型病毒性肝炎的临床分析  

A Clinical Analysis of Elderly Patients with Viral Hepatitis E

作　　者：齐俊英[1] 张振刚[1] 宋建新[1] 丁红芳[1] 陈红云[1] 宋佩辉[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院传染科,武汉430030

出　　处：《华中科技大学学报（医学版）》2002年第1期68-69,共2页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

摘　　要：为了解老年戊型病毒性肝炎的感染状况 ,对比分析了老年戊型肝炎 6 5例患者临床资料。老年组乏力及消化道症状重 ,黄疸上升幅度快而高 ,持续时间长 ,平均病程长达 (5 9.1± 18.7) d,较非老年组 (34 .9± 10 .1) d明显延长(P<0 .0 1) ;血清总胆红素为 (319.2 4± 10 2 .2 5 ) μmol/ L,明显高于非老年组 (178.15± 70 .43) μm ol/ L (P<0 .0 1) ;老年组重症肝炎发生率 (2 0 %)明显高于非老年组 (3.0 %) ,且死亡率高、并发症多 ,直接死因多为肝肾功能衰竭。结果表明 :戊型肝炎发病率呈逐年增高趋势 ,且老年患者多 ,病死率高 ,应特别注意。The clinical features of hepatitis E in elderly patients were investigated and the clinical symptoms of 65 elderly patients with hepatitis E analyzed comparatively. In the elderly group, symptoms of weakness and digestive problems were more severe, the jaundice risen more quickly and lasted longer (P<0.01). The average duration was longer apparently in the elderly group(59.11±18.66 days) than in the control group (34.87±10.05 days). The total serum bilirubin level in the elderly group (319.24±216.63 μmol/L) was higher than in the control group (178.15±115.47 μmol/L, P<0.01). Compared with the control, the elderly group had higher fulminant hepatitis rate (20 %) and higher mortality, and the direct causes of the death were the failure of liver and kidney. The results demonstrated that the occurrence rate of hepatitis E was increased yearly, and the elderly people suffered from hepatitis E frequently and get much higher mortality.

关 键 词：老年 重症肝炎 戊型病毒性肝炎 HE 

分 类 号：R512.6[医药卫生—内科学]