慢性肾衰致重症继发性甲状旁腺功能亢进的外科治疗(附10例报告)  

Treatment of CRF Patients with Severe Secondary Hyperparathyroidism by Parathyroidectomy Combined with Parathyroid Tissue Transplantation in Forearm (Report of 10 Cases)

作　　者：吴宏飞[1] 王笑云[2] 徐正铨[1] 钱立新[1] 张炜[1] 殷长军[1] 胡建民[2] 眭元庚[1] 

机构地区：[1]南京医科大学第一附属医院泌尿外科,江苏南京210029 [2]南京医科大学第一附属医院肾内科,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2002年第2期83-86,共4页Journal of Nanjing Medical University(Natural Sciences)

基　　金：国家自然科学基金资助项目(39800176)

摘　　要：目的：探讨甲状旁腺全切加前臂移植术治疗慢性肾衰致重症继发性甲状旁腺功能亢进的临床疗效。方法：对１９９５年１２月～２００１年９月经此方法治疗的１０例患者资料进行回顾性分析，并从定位诊断、手术适应证、围手术期处理等方面进行讨论。结果：１０例患者共切除增生的甲状旁腺３８枚，全部移植腺体成活，临床症状改善，各项化验结果逐步恢复正常。结论：对内科治疗无效的重症继发性甲状旁腺功能亢进进行甲状旁腺全切加前臂移植是一种安全、有效的治疗方法。Objective:To investigate the efficacy of parathyroide ctomy combined with parathyroid tissue transplantation in forearm in treatment o f CRF patients with severe secondary hyperparathyroidism (SHP). Methods:10 cases of CRF with SHP were treated with parathyroidectomy combined with par athyroid tissue transplantation in forearm from 1995 to 2001. The diagnosis, operation indication and peri-operation management of ten patients were discussed. Results:The hypertrophy parathyroids were totally resected in 10 CRF cases with SHP. All grafts were alive after transplantation. Symptoms of hyperpa rathyroidism disappeared and the various laboratory test turned to normal after operation. Conclusion:That surgical manipulation is safe and effectiv e in those CRF patients with severe SHP who failed in medical therapy.

关 键 词：继发性甲状旁腺功能亢进 慢性肾炎 外科手术 治疗 病例报告 

分 类 号：R653[医药卫生—外科学] R692.5[医药卫生—临床医学]