cTnI定量检测对心电图正常的胸痛患者的诊断价值  

DIAGNOSTIC VALUE OF THE QUANTATIVE TEST OF SERUM CTNI IN CHEST PAIN PATIENTS WITH NORMAL ELECTROCARDIOGRAM

作　　者：石奇松[1] 俞红[1] 张继才[1] 许金鹏[1] 姚青海[1] 杨菁[1] 石仲仁[1] 张勇[1] 

机构地区：[1]河北省保定市第二医院心内科,071051

出　　处：《中国煤炭工业医学杂志》2001年第12期962-963,共2页Chinese Journal of Coal Industry Medicine

摘　　要：目的　本研究旨在探讨血清肌钙蛋白Ⅰ (cTnI)定量检测对心电图正常的胸痛患者的诊断价值。方法　对 47例临床怀疑心绞痛而无发作时心电图ST段演变的患者进行血清cTnI定量检测 ,并行冠状动脉造影 ,将cTnI定量结果同冠脉内病变进行对比分析。结果　 47例患者中 ,A组 32例 (68.1 % ) ,cTnI 0 .0 2～ 0 .63ng/ml,B组 1 5例 (31 .9% ) ,cTnI<0 .0 2ng/ml,冠状动脉造影提示A组中冠脉正常及Ⅰ型病变者 7例 (2 1 .9% ) ,Ⅱ型病变者 2 5例 (78.1 % )。B组中冠状动脉正常及Ⅰ型病变患者 1 3例 (86 .7% ) ,Ⅱ型病变者 2例 (1 3 .3 % )。A组中Ⅱ型病变的患者明显高于B组 (P <0 .0 1 )。B组中冠状动脉正常及Ⅰ型病变患者明显高于Ⅱ型病变者 (P <0 .0 1 )。结论　cTnI定量检测值同冠状动脉造影显示冠脉内斑块形态和狭窄程度有密切关系 ,cTnI定量检测对诊断冠心病、心绞痛具有较好的临床价值。Objective To discuss the diagnostic value of the quantative test of serum cardiac troponin I (cTnI) in chest pain patients with natural electrocardiogram. Methods 47 patients, who were suspicious of angina, received serum cTnI test and coronary angiography. The test results and the coronary lesions were contrastively analyzed. Results Among 47 cases, group A consisting of 32 (68.1%) showed cTnI 0.02～0.63ng/ml, and group B consisting of 15 (31.9%) showed cTnI<0.02ng/ml. The coronary angiography indicated that in group A 7 cases (21.9%) had normal coronary artery or type I lesions and 25 cases (78.1%) showed type Ⅱ lesions, while in group B 13 cases (86.7%) had normal coronary artery or type I lesions and 2 cases (13.3%) showed type Ⅱ lesions. The patients in group A had more type Ⅱ lesions than those in group B (P<0.01). Group B contained more patients with natural coronary artery and type I lesions than those with type Ⅱ lesions (P<0.01). Conclusion Serum cardiac troponin I is closely associated with the plaque configuration and the severity of coronary lesions. Therefore, cTnI has clinical value in the diagnosis of angina and coronary heart disease.

关 键 词：肌钙蛋白-1 胸痛 冠状动脉造影 诊断 心电图 心绞痛 

分 类 号：R541.4[医药卫生—心血管疾病] R816.2[医药卫生—内科学]