多种神经活性物质在幼年猫和鸡视网膜神经细胞中的共存(简报)  

THE COEXISTENCE OF MULTI-NEUROACTIVE SUBSTANCES IN NEURONS OF THE DEVELOPING CAT AND CHICKEN RETINAS

作　　者：王厚华[1] 吕建利[1] 

机构地区：[1]中国科学院上海生理研究所

出　　处：《实验生物学报》1991年第4期423-429,共7页Acta Biologiae Experimentalis Sinica

基　　金：国家自然科学基金

摘　　要：视网膜起源于前脑泡,结构简单层次分明,因此常被视为脑的简化模型。但近期工作证明,视网膜包含的神经活性物质(神经递质、调质和神经肽)种类之多、分布之复杂并不亚于脑。尤其是无长突细胞不仅包含多种递质和肽类,而且还有递质与肽类或肽类与肽类在一个细胞中的共存。对视网膜神经递质、调质和神经肽的研究将是探索脑奥秘的有效途径。An improved post-embedding immunocytochemical technique was used to examine the coexistence of multi-neuroactive substances in neurons of young cat and newly hatched chicken retinas. We found that two classical neurotransmitters-glycine (Gly) and r-aminobutyric acid (GABA) and one neuropeptide, neurotensin (NT) were located in the amacrine cells of cat and chicken retinas. Among them, some cells contain Gly and GABA (GIy/GABA AC), some cells contain Gly and NT (Gly/NT AC) or GABA and NT (GABA/NT AC), and the other cells, a few of them contain Gly, GABA and NT (Gly/GABA/NT AC). In addition, two classical neurotransmitters Gly and GABA were also located or coexisted in the horizontal cells of cat retina, These results indicated that the coexistence of two neurotransmitters or one neurotransmitter and one neuropeptide or two neurotransmitters and one neuropeptide was presented in neurons of developing can and chicken retinas.

关 键 词：视网膜 猫 鸡 神经 活性物质 细胞 

分 类 号：Q952.5[生物学—动物学]