小儿支气管哮喘特异性免疫治疗及亚高原地区常见吸入过敏原的调查研究  

Specific immune Treatment of Children asthmus and investigation to absorbed allergens of sub-plateau zone

作　　者：杨玉林[1] 周有祥[1] 潘虹 戴时新 杨正芬 

机构地区：[1]贵州省兴义市人民工人医院儿科,562400

出　　处：《贵州医药》2002年第2期123-125,共3页Guizhou Medical Journal

基　　金：贵州省黔西南州科技局资金资助 (赞助号

摘　　要：目的探讨特异性免疫治疗 (脱敏治疗 )小儿哮喘的疗效。了解亚高原地区常见吸入过敏原与小儿哮喘的关系。方法 116例小儿哮喘随机抽出 78例 ,作过敏原检测 ,以阳性的 6 2例为治疗组 ,剩余的 38例及阴性的 16例作对照组 ,治疗组采用常规哮喘治疗加脱敏治疗 ,对照组仅作常规治疗。测第一秒时间肺活量 (FEV1 0 )判断疗效 ,并对该地区常见吸入过敏原与小儿哮喘的关系进行总结。结果治疗组总有效率为 98 38% ,对照组为 85 19% ,X =5 36 ,P <0 0 5 ,差异有显著意义 ;测FEV1 0 ,经比较 ,治疗前t=1 5 45 ,差异无显著意义 ,治疗后比较t=4 6 3,P <0 0 1,差异有极显著意义 ;治疗组复发 2例 ,复发率 3 2 3% ,对照组复发 2 1例 ,复发率 38 88% ;18种过敏原检测阳性率为79 4% ,以尘螨最高为 76 9%。结论 (1)脱敏治疗小儿哮喘疗效肯定 ,复发少 ;(2 )亚高原地区小儿哮喘过敏原检测阳性率高 ,以尘螨最为常见。Objective To research the treating effect of early childhood sathma by specific immune. Methods 78 cases of 116 cases with asthmus were detected by allergens. Take 62 cases as treating group, the remainders and the negative to allergen as controlled group, the former under routine treatment and specific immune treatment, the latter only under routine treatment, FEV 1.0 judge the effect. Results The effect of treating group was more significant than controlled group( P <0.05).The treated recurrence 2cases, incidence was 3.23%, the controlled recurrence 21 cases, incidence is 38.88%, the positive 79.48% of 18 checked allergens, special in Pyroglyphidae, it was highest to 76.1%. Conclusion Specific immune treatment to early childhood asthma was very effective and recurrence is less than controlled group's.

关 键 词：支气管哮喘 持异性免疫治疗 过敏原吸入 亚高原地区 治疗 调查研究 儿童 

分 类 号：R725.622.5[医药卫生—儿科]