肺心病患者体内TNF、TXB2、PGFla变化及临床意义  

The clinic value and change of plasma TNF, TXB_2 and PGFIa in patients with chronic pulmonary heart disease

作　　者：丁黎萍[1] 余黔灵[2] 

机构地区：[1]贵阳市第一人民医院呼吸科,550001 [2]贵阳市第一人民医院检验科,550001

出　　处：《贵州医药》2002年第2期107-108,共2页Guizhou Medical Journal

摘　　要：目的探讨慢性肺源性心脏病 (简称肺心病 )体内肿瘤坏死因子 (TNF) ,血栓素 β2(TXB2 ) ,6 酮 前列腺素 (PGFla)的变化和临床意义。方法分别抽取肺心病急性加重期及缓解期晨起空腹血 ,用GD 40 0 a计数器 ,通过放免法测定血浆中TNF ,TXB2 及PGFla的含量。结果治疗后TNF、TXB2 降低 ,PGFla升高。结论肺心病体内TNF、TXB2 、PGFla含量变化 ,可作为判断病情严重程度的实验指标。Objective To evaluate the clinical value and change of plasma TNF, TXB 2 and PGFIa in patients with chronic pulmonary heart disease (CPHD). Methods The plasma TNF TXB 2 and PGFIa were measured with DG-400-a calculator by radioimmunoassary in the cases during acure and revive CPHD . Results The plasma TNF and TXB 2 decreased PGFIa increased after the cases with CPHD were relieved. Conclusion The change of the plasma TNF, TXB 2 and PGFIa in CPHD can be judged how extent the cases are senous.

关 键 词：肺心病 肿瘤坏死因子 血栓素B2 6-酮-湔列腺素 临床意义 

分 类 号：R541.5[医药卫生—心血管疾病]