β-内啡肽在实验性内异症不孕模型中的变化  

The Variation of β-EP and Sex Hormones in Endometriosis-associated-infertility

作　　者：徐琳[1] 王秀丽[1] 单朝屏[1] 张林[2] 

机构地区：[1]昆明医学院第一附属医院妇产科,昆明650032 [2]昆明医学院第一附属医院病理科,昆明650032

出　　处：《昆明医学院学报》2002年第1期58-60,共3页Journal of Kunming Medical College

摘　　要：通过对实验性子宫内膜异位症模型和子宫内膜异位症不孕模型造模前、后 β -EP测定 ,以探讨 β-EP在内异症不孕发生中的可能作用 .方法 :制备内异症不孕和内异症的动物模型 ,分别测定造模前、后血β-EP水平 ,进行对比研究 .结果 :造模后与造模前相比 ,内异症和内异症不孕兔血 β -EP水平分别升高1 72倍和 1 4 2倍 (P <0 0 5 ) ,造模后 ,内异症不孕兔 β -EP水平高于内异症兔 (P <0 0 5 ) .结论 :内异症状态下 ,可能出现 β -EP的高分泌 ,高水平的 βIn order to find out the possible function of Beta-endorphin(β-EP) in the aetiology of endometriosis-associated-infertility(EAI) and to develop a new way to treat the EAI, we measured the concentration of β-EP in the blood of EAI and endometriosis(EMT) hares. First, we detected the concentration of β-EP before and after the making model. There is a significantly high level of β-EP in EAI and EMT hares contrast to that before the making model. We also found the level of β-EP in EAI hares is higher than the EMT hares(P>0 05). β-EP maybe is one of the possible causes which result in the EAI.

关 键 词：子宫内膜异位症 不孕症 兔 Β-EP 动物模型 Β-内啡肽 

分 类 号：R711.71[医药卫生—妇产科学] R711.6[医药卫生—临床医学]